Nrf2 as a modulator of oxidative stress
نویسندگان
چکیده
Nrf2 is active protein presents in the cytoplasm cells of body. In presence an activators, can enter nucleus which bind to Antioxidant Responses Elements (ARE) or otherwise named human ARE (hARE) control whole antioxidants activity cell. Many factors may contribute defective overwhelmed cellular activities for instances aging and damages. These damages be produced by free radicals oxidative stress. mechanism, if activated nucleus, caused production collaborative enzymes especially: catalase, glutathione (GLT) superoxide dismutase (SOD) as a responsible detoxification radical inside cells.
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ژورنال
عنوان ژورنال: Al-?ul?m al-?aydal?niyya?
سال: 2022
ISSN: ['1815-0993']
DOI: https://doi.org/10.32947/ajps.v21i4.798